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BPS BPS-Pharmacotherapy Exam Syllabus Topics:

BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

Question 1

From ethical and scientific validity standpoints, in addition to double blinding, which of the following research designs is best for determining a new medication's relative efficacy in treating acute stroke?

A. Parallel design comparing the new therapy with the best standard therapy
B. Placebo-controlled, crossover design
C. Placebo-controlled, randomized, parallel design
D. Crossover design comparing the new therapy with the best standard therapy

Question 2

What is the most appropriate source for identifying the generic name, classification, and adverse effects of a foreign brand-name medication?

A. American Hospital Formulary Service Drug information
B. Micromedex
C. Drug Facts & Comparisons
D. Martindale: The Complete Drug Reference

Question 3

When low molecular weight heparin is prescribed, in which of the following patient populations would monitoring anti-factor-Xa levels be reasonable to consider?

A. Protein C and Protein S deficiencies
B. Anticardiolipin antibody syndrome
C. Significant renal impairment
D. Past history of GI bleeding

Question 4

A 59-year-old patient who is HIV-positive is receiving darunavir and ritonavir as part of a highly active antiretroviral therapy program. Which herbal supplement is contraindicated for this patient because it would decrease darunavir concentrations?

A. St. John's wort
B. Saw palmetto
C. Echinacea
D. Kava kava

Question 5

A study shows that the participants who received 6 months of a new oral anticoagulant after a venous thromboembolism were randomized to continue with the new oral anticoagulant (n =
612) or to placebo (n = 611) for 18 months. Thromboembolism recurred in 12 subjects in the new oral anticoagulant group and 71 subjects in the placebo group (hazard ratio 0.17; 95% CI, 0.09-
0.30; p < 0.001).
Which of the following statements regarding these results is correct?

A. The new oral anticoagulant reduces the relative risk of a secondary venous thromboembolism by 17% compared to placebo.
B. The new oral anticoagulant reduces the relative risk of a secondary venous thromboembolism by 9.6% compared to placebo.
C. The new oral anticoagulant reduces the relative risk of a secondary venous thromboembolism by 83% compared to placebo.
D. The difference between the new oral anticoagulant and placebo in the secondary prevention of venous thromboembolism is not statistically significant.

Solutions: